Active Clinical Trials

For information regarding clinical trials please contact:

Kristy Averette, MSN, RN, CCRP
Research Practice Manager
Phone: 919-681-5797 

Advanced Solid Tumors

  • A Study Evaluating the Safety and Efficacy of ENV-101 (Taladegib) in Patients with Advanced Solid Tumors Harboring PTCH1 Loss of Function Mutations.


Advanced Skin Cancers

  • A Phase 1B/2 Study of RP1 in Solid Organ Transplant Patients with Advanced Cutaneous Malignancies.


Hidradenitis Suppurativa (HS)


  • Biorepository of Patients with Hidradenitis Suppurativa (HS): Determination of potential predictors and moderators of treatment response in patients with HS.


  • A Study to Test the Long-term Treatment of Bimekizumab in Study Participants with Moderate to Severe Hidradenitis Suppurativa (BE HEARD EXT).


Atopic Dermatitis/ Eczema

  • A Study to Evaluate Rocatinlimab (AMG 451) in Adolescent Subjects with Moderate-to-severe Atopic Dermatitis (AD) (ROCKET-ASTRO).


  • A Study Assessing Rocatinlimab (AMG 451) Monotherapy in Moderate-to-severe Atopic Dermatitis (AD) (ROCKET-Horizon) (ROCKET-Horizon).


  • Dupilumab in Adolescent and Adult Skin of Color Participants: Open-label Moderate-to-severe Eczema Trial (DISCOVER).



  • A Study to Evaluate Effectiveness and Safety of BMS-986322 in Participants With Moderate-to-Severe Psoriasis.



  • A Study to Evaluate Efficacy and Safety of Deucravacitinib in Participants With Active Discoid and/​or Subacute Cutaneous Lupus Erythematosus (DLE/​SCLE).


  • A Study to Assess the Efficacy and Safety of BIIB059 (Litifilimab) in Participants With Active Subacute Cutaneous Lupus Erythematosus (SCLE) and/​or Chronic Cutaneous Lupus Erythematosus (CCLE) With or Without Systemic Manifestations and Refractory and/​or Intolerant to Antimalarial Therapy (AMETHYST).