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Welcome to the Department of Dermatology

at Duke University Medical Center:

advancing a tradition of excellence in

Teaching, Investigating and Caring.

Department News

Dermatology Welcomes a New Clinician

Tarannum Jaleel, MD, graduated with honors from the University of Alabama at Birmingham in 2007, where she majored in Biophysics with a minor in Spanish.  she was subsequently selected to the Fulbright Scholar Program in 2007, which supported her work with the European Institute of Women's Health in Ireland.  She completed her medical school education at the University of Alabama Birmingham School of Medicine in 2012 and was elected to Alpha Omega Alpha.  She has completed Lumbreras course on tropical medicine in Lima, Peru in 2012 and has returned for several tropical dermatology electives subsequently during her training.  Following internship at the Boston University Medical Center, she completed her dermatology residency at her alma mater in 2016, where she received the Walter P. Little award for her leadership qualities and dedication to the profession.  In August, she will join the faculty of Duke Dermatology, where she will pursue her clinical and research interest in autoimmunity, oncodermatology, and immunotherapeutics.  She is also enrolled in the DUSOM's Clinical Research Training Program (CRTP) to pursue a Master of Health Sciences in Clinical Research.

Resident wins Presentation Prize

Dr. Ryan Thorpe, one of our second year residents, presented a case at the Resdient Sympsoium at the NC Dermatology Association meeting this past weekend in Willaimsburg, VA.  He was awarded first place for the best resident presentation.

We have a STAR

Dr. Terry Lechler's STAR Program aplication was approved by the National Institute of Arthritis and Musculoskeletal and Skin Diseases.  We congratulate him on this achievement.

Post-Doc Wins Poster Prize

Jutamas Suwanpradid, PhD from Dr. Amanda MacLeod's Lab won the Poster Prize at the Duke Innate Immunity Group Symposium in the Postdoctorate Category.  Together with Michael Shih, Tameika Phillips, Bin Yang, Anastasiya Birukova, Loretta Que, Robert Tighe and Amanda MacLeod, the presentation was entitled, “Arginase1/iNOS imbalance mediates contact hypersensitivity responses.”

Pinnell Center Symposium October 28, 2016

Our annual Pinnell Center Symposium will be occurring October 28th.  We have three noteworthy presenters, Dr. Todd Ridky from the University of Pennsylvania, Dr. Dennis Roop from the University of Colorado Denver, and Dr. Niroshana Anandasabapathy from Harvard Medical School.  Click on their names to view their websites.

Dermatology Nursing Essentials

Our very own Edna Atwater is the primary author of a book chapter.  The third edition of "Dermatology Nursing Essentials" was officially released last month and Edna along with co-author Penny Jones wrote Chapter 23, Wound Healing.

Amanda MacLeod, MD and her lab have received the Duke Cancer Institute Pilot Project Award for their studies "Novel Regulation of Cutaneous DNA Repair by Immune Cells."

Jonathan Cook, MD has been named Newsweek Magazine's "Top Doctors for Cancer."

 

 

 

 

 

Jennifer Zhang, PhD has received an RO3. The title of her RO3 is “The role of MALT1 in Melanoma Growth and Tumorigenesis.”

 

 

 

 

 

 

 

 

 

Terry Lechler, PhD has received a RO1. The title of his RO1 is “Role of Cell Adhesion and the Cytoskeleton in Epidermal Integrity.”

Elise Olsen, MD has been named Newsweek Magazine's "Top Doctors for Cancer."

Over the past several years, Neil Prose, MD has helped to create instructional videos on doctor-patient communication for neurosurgeons, cardiothoracic surgeons, ENT surgeons, and urologists.  The nuerosurgery videos are now the core of a national course for residents in neurosurgery, and the success of that program was documented in a recent article in the Journal of Surgical Education.  In addition, several of the videos are available online to registrants of the Open School of the Institute of Health Care Improvement (IHI).  Courses at the school reach 250,000 students and residents in 76 countries.

Latest Faculty Speaking Engagements

	Amanda MacLeod, MD 2016 Duke Innate Immunity Group Symposium in Durham, NC - June 17, 2016 --Innate Immunity and Inflammation
	Terry Lechler, PhD Gordon Research Seminar on Cell Polarity Signaling in West Dover, VT -- June 11-12, 2106 --Spindle orientation in epidermal development and disease
	M Angelica Selim, MD 31st International Congress of the International Academy of Pathology and 28th Congress of teh European Society of Pathology -- September 25-29, 2016 --Vulvar Pathology and New Technologies
	Neil Prose, MD DI Skin Hospital in Kathmandu, Nepal -- June -- set up program whereby pediatric dermatologists from US volunteer to train pediatric residents (Society for Pediatric Dermatology & Health Volunteers Overseas) --series of lectures

Latest Faculty Publications

Olsen EA, ed. Issue of Dermatologic Clinics on Cutaneous Lymphoma.   Olsen EA. Evaluation, diagnosis and staging of cutaneous lymphoma. Accepted for publication Dermatologic Clinics.   Olsen EA, Hodak E, Anderson T, Carter JB, Henderson M, Cooper K, Lim HW.  Guidelines for Phototherapy of Mycosis Fungoides and Sezary Syndrome: A Consensus Statement of the United States Cutaneous Lymphoma Consortium (USCLC).  Accepted for publication, J Am Acad Dermatol.

Hoang M, Selim MA, eds. Vulvar Pathology. Springer, 2015 edition.

Pomerantz H, Hogan D, Eilers D, Swetter SM, Chen SC, Jacob SE, Warshaw EM, Stricklin G, Dellavalle RP, Sidhu-Malik N, Konnikov N, Werth VP, Keri J, Lew R, Weinstock MA; for the Veterans Affairs Keratinocyte Carcinoma Chemoprevention (VAKCC) Trial Group. Long-term Efficacy of Topical Fluorouracil Cream, 5%, for Treating Actinic Keratosis: A Randomized Clinical Trial. JAMA Dermatol. 2015 May 7. doi:10.1001/jamadermatol.2015.0502.

Kim JK, Ahmad A, Selim MA, Olsen EA, Cardones AR. Disseminated Cutaneous Cytomegalovirus Infection Following Total Body Electron Beam Irradiation for Mycosis Fungoides. JAMA Dermatol. 2015 Aug 12. [Epub ahead of print] No abstract available. Lee SY, Cardones AR, Doherty J, Nightingale K, Palmeri M. Preliminary Results on the Feasibility of Using ARFI/SWEI to Assess Cutaneous Sclerotic Diseases. Ultrasound Med Biol. 2015 Aug 7. doi:10.1016/j.ultrasmedbio.2015.06.007 [Epub ahead of print]. Poster - SID Annual Mtg., Atlanta, GA – May 2015 -- Retrospective study comparing outcomes among patients receiving rituximab vs conventional adjuvant therapy for pemphigus vulgaris.  -- Patients with sorafenib induced drug eruptions can be successfully re-challenged.  -- Novel imaging techniques for quantifying cutaneous sclerosis.

Poster - SID Annual Mtg., Atlanta, GA – May 2015 -- A counter-intuitive role for caspase-3 in promoting genetic instability and skin carcinogenesis. Liu X, He Y, Li F, Huang Q, Kato TA, Hall RP, Li CY.  Caspase-3 Promotes Genetic Instability and Carcinogenesis. Mol Cell. 2015 Apr 8. PMID; 25866249 doi: 10.1016/j.molcel.2015.03.003 Liu X, He Y, Li F, Huang Q, Kato TA, Hall RP, Li CY.  Caspase-3 Promotes Genetic Instability and Carcinogenesis. Mol Cell. 2015 Apr 8. PMID; 25866249 doi: 10.1016/j.molcel.2015.03.003

Poster - SID Annual Mtg., Atlanta, GA – May 2015 -- A counter-intuitive role for caspase-3 in promoting genetic instability and skin carcinogenesis. Xinjian Liu, Fang Li, and Chuan-Yuan Li Liu X, He Y, Li F, Huang Q, Kato TA, Hall RP, Li CY.  Caspase-3 Promotes Genetic Instability and Carcinogenesis. Mol Cell. 2015 Apr 8. PMID; 25866249 doi: 10.1016/j.molcel.2015.03.003

Poster - SID Annual Mtg., Atlanta, GA – May 2015 -- ENTPD1 and PD-1/PD-1 ligands are highly expressed by skin-resident immune cells in subsets of human SCC.

Chen Y, Fang Q, Zang Z, Zhang Y, MacLeod AS, Hall RP, Liedtke W.  Transient receptor potential vanilloid 4 ion channel functions as a pruriceptor in epidermal keritinocytes to evoke histaminergic itch.  First published on 2016 Mar 9. doi: 10.1074/jbc.M116.716464   Poster - SID Annual Mtg., Atlanta, GA – May 2015 -- Retrospective study comparing outcomes among patients receiving rituximab vs conventional adjuvant therapy for pemphigus vulgaris. -- Novel imaging techniques for quantifying cutaneous sclerosis.   Liu X, He Y, Li F, Huang Q, Kato TA, Hall RP, Li CY.  Caspase-3 Promotes Genetic Instability and Carcinogenesis. Mol Cell. 2015 Apr 8. PMID; 25866249 doi: 10.1016/j.molcel.2015.03.003

Lechler T, "Studying Cell Biology in the Skin" in Molecular Biology of the Cell, commissioned review   Poster - SID Annual Mtg., Atlanta, GA – May 2015 -- FRA1 plays an essential role in skin, head and neck cancer cell growth and migration . --NuMA/microtubule interactions are critical for asymmetric cell divisions and epidermal morphogenesis.

Lai C, August S, Albibas A, Behar R, Cho SY, Polak ME, Theaker J, MacLeod AS, French RR, Glennie M, Al-Shamkhani A, Healy E. O40+ regulatory T cells in cutaneous squamous cell carcinoma suppress effector T cell responses and associate with metastatic potential.  Accepted 2016 in Clinical Cancer Research.   Chen Y, Fang Q, Zang Z, Zhang Y, MacLeod AS, Hall RP, Liedtke W.  Transient receptor potential vanilloid 4 ion channel functions as a pruriceptor in epidermal keritinocytes to evoke histaminergic itch.  First published on 2016 Mar 9. doi: 10.1074/jbc.M116.716464   Poster -- SID Annual Mtg., Atlanta, GA – May 2015 -- ENTPD1 and PD-1/PD-1 ligands are highly expressed by skin-resident immune cells in subsets of human SCC.   MacLeod AS, Mansbridge, JN. The Innate Immune System in Acute and Chronic Wounds.  Advances in Wound Care. eprint 2015 Mar 25.  doi: 10.1089/wound.2014.0608.

Poster - SID Annual Mtg., Atlanta, GA – May 2015 -- FRA1 plays an essential role in skin, head and neck cancer cell growth and migration. --ENTPD1 and PD-1/PD-1 ligands are highly expressed by skin-resident immune cells in subsets of human SCC. --miR29b1 plays an important role in epidermal cell growth and survival.