Kimberly Breglio

Kimberly Breglio

Third Year Resident

Start Year

2020

What are your career interests?

I am interested in cutaneous oncology, immunology, and autophagy. In my career, I hope to spend some time doing procedures and also time doing research in a team science model. 

Why did you choose Duke for residency training?

I chose Duke for residency because of the breadth of training, especially exposure to diverse skin types, which will help me make dermatologic diagnoses in any patient population. Both the Dermatology Department and Duke University have incredible research resources, so it will be an ideal place to begin my research career. When I interviewed, the residents were funny, kind, and friendly, so I knew Duke would be a supportive learning atmosphere. My family was excited to move to an area with lower cost of living and great access to the mountains and the beach.

Education & Training

Undergraduate:  McGill University, Montreal, QC, Canada, B.Sc.: Ecological Determinants of Health (Cell), 2009

Medical School: Penn State College of Medicine, Hershey, PA, M.D., 2019

Graduate School: University of Oxford, Oxford, UK, D.Phil., 2018

Internship: Pediatrics, University of North Carolina, Chapel Hill, NC, 2019-2020

Residency: Dermatology, Duke University, 2020-Present

Awards & Honors

  • National Institutes of Health Summer Research Mentor Award, 2017               
  • Merton College Graduate Research Grant, 2017
  • Conference on Retroviruses and Opportunistic Infections Young Investigator Scholarship, 2015
  • Benjamin H. Kean Travel Fellowship in Tropical Medicine, 2014
  • Tylenol Future Care Scholarship, 2014
  • Ballentine Endowment for Medical Student Work in the Arts, 2014
  • Association of Pathology Chairs Honor Society, 2013
  • Community Service Award Winner, Milton S. Hershey Medical Center, 2012
  • Mark J. Young International Health Policy Scholarship, 2012
  • The Doctors Kienle Center for Humanistic Medicine Grant for Service to the Underserved, 2011

Publications & Presentations

Publications

  • J.M. Sa, S.R. Kaslow, M.A. Krause, V.A. Melendez-Muniz, R.E. Salzman, W.A. Kite, M. Zhang, R.R. Moraes Barros, J. Mu, P.K. Han, J.P. Mershon, C.E. Figan, R.L. Caleon, R.S. Rahman, T.J. Gibson, C. Amaratunga, E.P. Nishiguchi, K.F. Breglio, T.M. Engels, S. Velmurugan, S. Ricklefs, J. Straimer, N.F. Gnadig, B. Deng, A. Liu, A. Diouf, K. Miura, G.S. Tullo, R.T. Eastman, S. Chakravarty, E.R. James, K. Udenze, S. Li, D.E. Sturdevant, R.W. Gwadz, S.F. Porcella, C.A. Long, D.A. Fidock, M.L. Thomas, M.P. Fay, B.K.L. Sim, S.L. Hoffman, J.H. Adams, R.M. Fairhurst, X.Z. Su, T.E. Wellems. Artemisinin resistance phenotypes and K13 inheritance in a Plasmodium falciparum cross and Aotus model. PNAS. 2018 Dec 4.
  • K.F. Breglio, R. Amato, R. Eastman, P. Lim, J.M. Sa, R. Guha, S. Ganesan, D.W. Dorward, C. Klumpp-Thomas, C. McKnight, R.M. Fairhurst, D. Roberts, C. Thomas, A.K. Simon. A single nucleotide polymorphism in the Plasmodium falciparum atg18 gene associates with artemisinin resistance and confers enhanced parasite survival under nutrient deprivation. Malaria J. 2018 Oct 26.
  • D.C. Hsu*, K.F. Breglio*, L. Pei, C.S. Wong, B.B. Andrade, V. Sheikh, M. Smelkinson, C. Petrovas, A. Rupert, L. Gil-Santana, A. Zelazny, S.M. Holland, K. Olivier, D. Barber, I. Sereti. Emergence of polyfunctional cytotoxic CD4+ T cells in Mycobacterium avium Immune Reconstitution Inflammatory Syndrome in Human Immunodeficiency Virus-infected patients. Clinical Infectious Diseases. 2018 March 10.
  • K.F Breglio, R.S. Rahman, J.M. Sa, A. Hott, D.J. Roberts, T.E. Wellems. Kelch mutations in Plasmodium falciparum protein K13 do not modulate dormancy after artemisinin exposure and sorbitol selection in vitro. Antimicrob Agents Chemother. 2018 Feb 20.
  • K.F. Faldetta, S.A. Norton. The toxic touch. JAMA Dermatology. 2016 Jul 1:152(7):797.
  • D.C. Hsu, K.F. Faldetta, L. Pei, V. Sheikh, N.S. Utay, G. Roby, A. Rupert, A.S. Fauci, I. Sereti. A paradoxical treatment for a paradoxical condition: infliximab use in three cases of mycobacterial IRIS. Clin Infect Dis. 2016 Jan 15:62(2):258-61.
  • M.A. Santos, K.F. Faldetta, A.L. Zaenglein. Yaws: Rebound of a forgotten disease. Global Dermatology. 2(3):138-142, 2015.
  • K.F. Faldetta, M.A. Santos, J.E. Smucker, S.A. Norton, A.L. Zaenglein. Buruli ulcer: a review. Global Journal of Dermatology & Venereology. 2:69-75, 2014.
  • K.F. Faldetta, S. Kattakuzhy, H.W. Wang, I. Sereti, V. Sheikh. Cytomegalovirus immune reconstitution inflammatory syndrome manifesting as acute appendicitis in an HIV-infected patient. BMC Infectious Diseases. 2014 June 9:14:313.
  • K.F. Faldetta, D.A. Reighard, K.L. Dickinson, C.Q. Wang. Assessing domestic water quality in Belen municipality, Iquitos, Peru. Journal of Water, Sanitation, and Hygiene for Development. March 2014.

Presentations

  • K.F. Breglio, R. Amato, P. Lim, R.T. Eastman, D. Roberts, C.J. Thomas, A.K. Simon, Phenotypic changes and drug sensitivity associated with an atg18 mutation in Plasmodium falciparum. American Society of Tropical Medicine and Hygiene Annual Meeting, Baltimore, MD. Nov 2017 (Oral presentation).
  • K.F. Breglio, R.T. Eastman, D. Roberts, C.J. Thomas, A.K. Simon. Metabolic changes and drug sensitivity associated with a genetic polymorphism in atg18 in Plasmodium falciparum. Autophagy in Stress, Development and Disease, Gordon Research Conference, Barga, Italy. March 2018.
  • K.F. Breglio, R. Amato, P. Lim, D. Roberts, K. Simon, R. Fairhurst. Autophagy in artemisinin-resistant Plasmodium falciparum. Keystone Autophagy Network Integration in Health and Disease, Copper Mountain, CO. Feb 2017.
  • K.F. Breglio, D. Roberts, R. Fairhurst, K. Simon. A novel FACS method to detect autophagy in Plasmodium falciparum. American Society of Tropical Medicine and Hygiene Annual Meeting, Atlanta, GA. Nov 2016.
  • K.F. Faldetta, D.C. Hsu, V. Sheikh, G. Roby, K.N. Olivier, I. Sereti. Exuberant pathogen-specific Th1 CD4+ T-cell response in MAC-IRIS in HIV infection. Conference on Retroviruses and Opportunistic Infections, Seattle, WA. February 2015.
  • K.F. Faldetta, V. Sheikh, G. Roby, D.R. Prevots, I. Sereti, K.N. Olivier. Clinical characteristics of patients with Pulmonary MAC in a contemporary HIV+ cohort. American Thoracic Society, San Diego, CA. May 28, 2014 (Oral poster presentation).
  • K.F. Faldetta, D.A. Reighard, K.L. Dickinson, C.Q. Wang, D. George, W. Strosnider. The need for point of use water treatment in areas of peri-urban poverty: Case study outside Iquitos, Peru. American Society of Tropical Medicine and Hygiene Annual Meeting, Atlanta, GA. Nov 2012.
  • K.F. Faldetta and G.A. Pujalte. Effects of Exclusive Breastfeeding duration on child height in an impoverished coastal community in Ecuador. American Women’s Medical Association Annual Conference, Miami, FL. April 13, 2012.
  • K.F. Faldetta, J.N. Hernandez, and O.H. Branch. Prevalence of Plasmodium vivax and Plasmodium falciparum in pregnant women living in the Peruvian Amazon, a region of low transmission. American Society of Tropical Medicine and Hygiene Annual Meeting, Atlanta, GA. Oct 2010.
  • K.F. Faldetta, J.E. Kohler, A.L. Blass, M. Williams, E. Kelly, D.I. Soybel. Zinc Deficiency Causes Selective Modulation of Zinc Transporters Zip 10 and ZnT 1 in Murine Macrophages. Journal of Surgical Research, Jan 15, 2010.