Jeffery Kwock

Jeffery Kwock

Third Year Resident

Start Year

2020

What are your career interests?

General dermatology, immunodermatology, and medical dermatology

Why did you choose Duke for residency training?

I chose Duke for my Dermatology residency training because of the incredible sense of collegiality among residents and the world-class faculty.  Duke also offers numerous opportunities for residents to participate in both research and mentorship. 

Education & Training

Undergraduate: University of Hawaii at Manoa, BS Biology, 2013

Medical School: Duke University School of Medicine, MD, 2019

Internship: Internal Medicine, Duke University, 2019-2020

Residency: Dermatology, Duke University, 2020 - 2023

Awards & Honors

  • Palumbo Family Medical Scholarship, Duke University School of Medicine
  • William G. Anlyan Senior Merit Scholarship, Duke University School of Medicine
  • Alpha Omega Alpha Honor Medical Society, Duke University School of Medicine
  • Eugene A. Stead, Jr. Research Fellowship, Duke University School of Medicine
  • Phi Beta Kappa, University of Hawaii at Manoa

Publications & Presentations

Original Publications

  • Kwock JT, Handfield C, Suwanpradid J, et al.  IL-27 signaling activates skin cells to induce innate antiviral proteins and protects against Zika virus infection.  Sci Adv. 2020;6(14):eaay3245.
  • Amanda S. MacLeod & Jeffery T. Kwock.  Inflammation in Wound Repair: Role and Function of Inflammation in Wound Repair.  In: Kursad Turksen, 1st Ed.  Wound Healing: Stem Cells Repair and Regenerations, Basic and Clinical Aspects.  New Jersey: Wiley-Blackwell; 2018 p. 177-194.
  • Handfield C, Kwock J, MacLeod AS. Innate Antiviral Immunity in the Skin. Trends Immunol. 2018;39(4):328-40. Epub 2018/03/13. [PMID: 29526487].
  • Jeffery Kwock, Megan Casady, Chelsea Handfield, Amanda S. MacLeod, Michelle Pavlis.  A Trichogenic Tumor with Aggressive Features Initially Diagnosed as Basal Cell Carcinoma.  Dermatology Online J.  2018; 24(9).

Abstracts Accepted for Oral Presentation

  • Handfield C, Kwock J, Hoang P, MacLeod A.  Activation of Trpv1+ nociceptive fibers stimulates an innate antiviral immune response following skin injury.  In: Journal for Investigative Dermatology; May 2019; Chicago, IL.  Abstract: 663.
  • Suwanpradid J, Hoang P, Kwock J, Floyd L, Smith J, Kedl R, Atwater A, Rajagopal S, Corcoran D, MacLeod A.  IL-27 in macrophages mediates I cell survival and dermal cluster formation in allergic contact hypersensitivity.  In: Journal for Investigative Dermatology; May 2019; Chicago, IL.  Abstract: 010.
  • Kwock J, Handfield C, Suwanpradid J, Hoang P, Pontius L, MacLeod A.  Innate antiviral immunity is activated upon skin injury via an IL-27/STAT1 axis.  Paper presented at: Alpha Omega Alpha Honor Society Annual Scientific Research Symposium; Aug 3, 2018; Durham, NC.
  • Kwock J, Handfield C, Suwanpradid J, Hoang P, Pontius L, MacLeod A.  Innate antiviral immunity is activated upon skin injury via an IL-27/STAT1 axis.  In: Journal of Investigative Dermatology; May 2018; Orlando, Florida.  Abstract 926. 
  • Handfield C, Kwock J, Hoang P, Suwanpradid J, Han Q, Ji R, MacLeod A.  Activation of nociceptive fibers following acute skin injury triggers innate antiviral immunity.  In: Journal of Investigative Dermatology; May 2018; Orlando, Florida.  Abstract 1401.
  • Suwanpradid J, Hoang P, Pontius L, Kwock J, MacLeod A.  IL-27 signaling is relevant for IL-15 production and T cell cluster maintenance in allergic contact hypersensitivity.  In: Journal of Investigative Dermatology; May 2018; Orlando, Florida.  Abstract 087.
  • Kwock J, Handfield C, Suwanpradid J, Hoang P, Pontius L, MacLeod A.  Innate antiviral immunity is activated upon skin injury via an IL-27/STAT1 axis.  Paper presented at: Pinnell Center Works-in-Progrss; Mar 27, 2018; Durham, NC.
  • Kwock J, Handfield C, Mihai A, Pontius L, Mayock J, Yang B, McFadden M, Hoang P, Suwanpradid J, Horner S, MacLeod A.  Dynamic control of innate antiviral gene signatures in skin homeostasis and wound repair.  Paper presented at: Pinnell Center Symposium; Oct 13, 2017; Durham, NC.
  • Kwock J, Mihai A, Pontius L, Yang B, Maycock J, MacLeod A.  IL-27 signaling induces innate antiviral competence in skin wounds in a STAT1-dependent and INFNAR-independent manner.  Paper presented at: Duke Innate Immunology Group Symposium; June 7, 2017; Durham, NC.
  • Kwock J, Yang B, Maycock J, McFadden M, Suwanpradid J, Pontius L, Hoang P, Horner S, MacLeod AS.  IL-27 promotes innate immunity and antiviral competence in wounds.  Paper presented at: Symposium for Advanced Wound Care/Wound Healing Society Meeting; April 8, 2017; Durham, NC.
  • Kwock J, Yang B, Maycock J, McFadden M, Suwanpradid J, Pontius L, Hoang P, Horner S, MacLeod A. IL=27 signaling induced antiviral competence in skin wounds.  Paper presented at: Pinnell Center Works-in-Progress; Mar 28, 2017; Durham, NC. 

Abstracts Accepted for Poster Presentation

  • MacLeod AS, Kwock J, Handfield C.  Skinn Innate Antimicrobial Immunity is Regulated by IFN-Dependent and IFN-Independent Immunity and Protects Against Flavivirus Infection.  Paper presented at: Cytokines 2019; Oct 2019; Vienna, Austria.
  • Lei V, Kwock J, Kirchner S, Ling X, Corcoran D, MacLeod A.  Age and circadian regulation of cutaneous innate antimicrobial immunity.  Paper presented at: Children’s Health and Discovery Initiative Research Showcase; Oct 30, 2019; Durham, NC.
  • Handfield C, Kwock J, Hoang P, MacLeod A.  Activation of Trpv1+ nociceptive fibers stimulates an innate antiviral immune response following skin injury.  In: Journal for Investigative Dermatology; May 2019; Chicago, IL.  Abstract: 663.
  • Suwanpradid J, Hoang P, Kwock J, Floyd L, Smith J, Kedl R, Atwater A, Rajagopal S, Corcoran D, MacLeod A.  IL-27 in macrophages mediates I cell survival and dermal cluster formation in allergic contact hypersensitivity.  In: Journal for Investigative Dermatology; May 2019; Chicago, IL.  Abstract: 010.
  • Kwock J, Handfield C, Suwanpradid J, Hoang P, Pontius L, MacLeod A.  Innate antiviral immunity is activated upon skin injury via an IL-27/STAT1 axis.  In: Journal of Investigative Dermatology; May 2018; Orlando, Florida.  Abstract 926. 
  • Handfield C, Kwock J, Hoang P, Suwanpradid J, Han Q, Ji R, MacLeod A.  Activation of nociceptive fibers following acute skin injury triggers innate antiviral immunity.  In: Journal of Investigative Dermatology; May 2018; Orlando, Florida.  Abstract 1401.
  • Suwanpradid J, Hoang P, Pontius L, Kwock J, MacLeod A.  IL-27 signaling is relevant for IL-15 production and T cell cluster maintenance in allergic contact hypersensitivity.  In: Journal of Investigative Dermatology; May 2018; Orlando, Florida.  Abstract 087.
  • Kwock J, Handfield C, Mihai A, Pontius L, Maycock J, Yang B, Hoang P, Suwanpradid J, McFadden M, Horner S, Macleod A.  Regulation of innate antiviral gene signatures during wound repair.  Presented at: Keystone Symposia: Regulation and Dysregulation of the Innate Immune System; Feb 20, 2018; Vancouver, British Columbia, Canada.
  • Kwock J, Handfield C, Mihai A, Pontius L, Maycock J, Yang B, McFadden M, Hoang P, Suwanpradid J, Horner S, MacLeod A.  Regulation of innate antiviral gene signatures during wound repair.  Paper presented at: Regennext Symposium; Nov 3, 2017; Durham, NC.
  • Kwock J, Mihai A, Pontius L, Yang B, Maycock J, MacLeod A.  IL-27 signaling induces innate antiviral competence in skin wounds in a STAT1-dependent and INFNAR-independent manner.  Paper presented at: Duke Innate Immunology Group Symposium; June 7, 2017; Durham, NC.
  • Kwock J, Yang B, Maycock M, McFadden M, Suwanpradid J, Pontius L, Hoang P, Horner S, MacLeod A.  IL-27 promotes innate antiviral competence in wounds.  Paper presented at: Bernard D. Amos Poster Competition; May 2, 2017; Durham, NC.
  • Kwock J, Yang B, Maycock J, McFadden M, Suwanpradid J, Pontius L, Hoang P, Horner S, MacLeod A.  IL-27 promotes innate antiviral competence in wounds.  In: Journal of Investigative Dermatology; May 2017; Portland, OR.  Abstract 594. 
  • Pontius L, Suwanpradid J, Kwock J, Yang B, Maycock J, Kedl R, Hammer G, MacLeod A.  IL-27 signaling is essential for IL-15 production and mediates contact hypersensitivity.  In: Journal of Investigative Dermatology; May 2017; Portland, OR.  Abstract 609.