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Welcome to the Department of Dermatology

at Duke University Medical Center:

advancing a tradition of excellence in

Teaching, Investigating and Caring.

Department News

Dermatology Nursing Essentials

Our very own Edna Atwater is the primary author of a book chapter.  The third edition of "Dermatology Nursing Essentials" was officially released last month and Edna along with co-author Penny Jones wrote Chapter 23, Wound Healing.

Derm Next Door

Dr. Sinae Kane has posted new dermatology education videos to the YouTube channel Derm Next Door. You can check out the videos here.

Doctor: Protect Yourself from Sun's Harmful Rays

Dr. Sinae Kane is featured in an article in the Herald Sun talking about protecting your skin from the sun and that skin cancer is on the rise.  You can read the article here if you have a subscription.

Skin Has the Nerve to Tell You to Scratch

Dr. Wolfgang Liedtke, along with Dermatology's Drs. Jennifer Zhang, Amanda MacLeod, and Russell Hall, have identified a potential drug target in the skin for itchiness.  You can read more about their findings in the Duke Today article by Karl Bates.

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Faculty Awards

M. Angelica Selim, MD, in collaboration with Francisco Robles, PhD and WS Warren, PhD, has received the “Best Abstract Presentation” in the XXIII World Congress of the International Society for the Study of Vulvar Disease in New York City.  The title of their presentation is “Quantitative Molecular Imaging of Microscopic Pigment Chemistry in Female Genital Tract Melanocytic Lesions using Pump-Probe Laser Microsopy.”

 
Amanda MacLeod, MD and her lab have received the Duke Cancer Institute Pilot Project Award for their studies "Novel Regulation of Cutaneous DNA Repair by Immune Cells."
 
 
 
 
 
 

Jonathan Cook, MD has been named Newsweek Magazine's "Top Doctors for Cancer."
 
 
 
 
 
 
Jennifer Zhang, PhD has received an RO3. The title of her RO3 is “The role of MALT1 in Melanoma Growth and Tumorigenesis.”
 
 
 
 
 
 
 
 
 
Terry Lechler, PhD has received a RO1. The title of his RO1 is “Role of Cell Adhesion and the Cytoskeleton in Epidermal Integrity.”
 
 
 

 

Elise Olsen, MD has been named Newsweek Magazine's "Top Doctors for Cancer."

 

 

 

Dr. Neil ProseOver the past several years, Neil Prose, MD has helped to create instructional videos on doctor-patient communication for neurosurgeons, cardiothoracic surgeons, ENT surgeons, and urologists.  The nuerosurgery videos are now the core of a national course for residents in neurosurgery, and the success of that program was documented in a recent article in the Journal of Surgical Education.  In addition, several of the videos are available online to registrants of the Open School of the Institute of Health Care Improvement (IHI).  Courses at the school reach 250,000 students and residents in 76 countries.

Latest Faculty Speaking Engagements

Jennifer Powers, MD
SAWC in Atlanta, GA -- April 2016
-- Malignant and inflammatory wounds
 
 
 
 

 

 

Amanda MacLeod, MD

Society of Investigative Dermatology 75th Annual Meeting in Scottsdale, AZ - May 11-14, 2016
--Il-27 facilitates skin wound healing through induction of epidermal proliferation and host defense

2016 Duke Innate Immunity Group Symposium in Durham, NC - June 17, 2016
--Innate Immunity and Inflammation

 

Terry Lechler, PhD

Gordon Research Seminar on Cell Polarity Signaling in West Dover, VT -- June 11-12, 2106
--Spindle orientation in epidermal development and disease

 

 

Latest Faculty Publications

Olsen EA, ed. Issue of Dermatologic Clinics on Cutaneous Lymphoma.
 
Olsen EA. Evaluation, diagnosis and staging of cutaneous lymphoma. Accepted for publication Dermatologic Clinics.
 
Olsen EA, Hodak E, Anderson T, Carter JB, Henderson M, Cooper K, Lim HW.  Guidelines for Phototherapy of Mycosis Fungoides and Sezary Syndrome: A Consensus Statement of the United States Cutaneous Lymphoma Consortium (USCLC).  Accepted for publication, J Am Acad Dermatol.
Dr. Angelica SelimHoang M, Selim MA, eds. Vulvar Pathology. Springer, 2015 edition.
Dr. Navjeet Sidhu-MalikPomerantz H, Hogan D, Eilers D, Swetter SM, Chen SC, Jacob SE, Warshaw EM, Stricklin G, Dellavalle RP, Sidhu-Malik N, Konnikov N, Werth VP, Keri J, Lew R, Weinstock MA; for the Veterans Affairs Keratinocyte Carcinoma Chemoprevention (VAKCC) Trial Group. Long-term Efficacy of Topical Fluorouracil Cream, 5%, for Treating Actinic Keratosis: A Randomized Clinical Trial. JAMA Dermatol. 2015 May 7. doi:10.1001/jamadermatol.2015.0502.

Kim JK, Ahmad A, Selim MAOlsen EACardones ARDisseminated Cutaneous Cytomegalovirus Infection Following Total Body Electron Beam Irradiation for Mycosis Fungoides. JAMA Dermatol. 2015 Aug 12. [Epub ahead of print] No abstract available.

Lee SY, Cardones AR, Doherty J, Nightingale K, Palmeri M. Preliminary Results on the Feasibility of Using ARFI/SWEI to Assess Cutaneous Sclerotic Diseases. Ultrasound Med Biol. 2015 Aug 7. doi:10.1016/j.ultrasmedbio.2015.06.007 [Epub ahead of print].

Poster - SID Annual Mtg., Atlanta, GA – May 2015
-- Retrospective study comparing outcomes among patients receiving rituximab vs conventional adjuvant therapy for pemphigus vulgaris. 
-- Patients with sorafenib induced drug eruptions can be successfully re-challenged. 
-- Novel imaging techniques for quantifying cutaneous sclerosis.
 
Poster - SID Annual Mtg., Atlanta, GA – May 2015
-- A counter-intuitive role for caspase-3 in promoting genetic instability and skin carcinogenesis.

Liu X, He Y, Li F, Huang Q, Kato TA, Hall RP, Li CY.  Caspase-3 Promotes Genetic Instability and Carcinogenesis. Mol Cell. 2015 Apr 8. PMID; 25866249 doi: 10.1016/j.molcel.2015.03.003

Liu X, He Y, Li F, Huang Q, Kato TA, Hall RP, Li CY.  Caspase-3 Promotes Genetic Instability and Carcinogenesis. Mol Cell. 2015 Apr 8. PMID; 25866249 doi: 10.1016/j.molcel.2015.03.003
 

Poster - SID Annual Mtg., Atlanta, GA – May 2015 -- A counter-intuitive role for caspase-3 in promoting genetic instability and skin carcinogenesis. Xinjian Liu, Fang Li, and Chuan-Yuan Li

Liu X, He Y, Li F, Huang Q, Kato TA, Hall RP, Li CY.  Caspase-3 Promotes Genetic Instability and Carcinogenesis. Mol Cell. 2015 Apr 8. PMID; 25866249 doi: 10.1016/j.molcel.2015.03.003
 

Poster - SID Annual Mtg., Atlanta, GA – May 2015
-- ENTPD1 and PD-1/PD-1 ligands are highly expressed by skin-resident immune cells in subsets of human SCC.
 
 
 
 
Chen Y, Fang Q, Zang Z, Zhang Y, MacLeod AS, Hall RP, Liedtke W.  Transient receptor potential vanilloid 4 ion channel functions as a pruriceptor in epidermal keritinocytes to evoke histaminergic itch.  First published on 2016 Mar 9. doi: 10.1074/jbc.M116.716464
 
Poster - SID Annual Mtg., Atlanta, GA – May 2015
-- Retrospective study comparing outcomes among patients receiving rituximab vs conventional adjuvant therapy for pemphigus vulgaris.
-- Novel imaging techniques for quantifying cutaneous sclerosis.
 
Liu X, He Y, Li F, Huang Q, Kato TA, Hall RP, Li CY.  Caspase-3 Promotes Genetic Instability and Carcinogenesis. Mol Cell. 2015 Apr 8. PMID; 25866249 doi: 10.1016/j.molcel.2015.03.003
 
Lechler T, "Studying Cell Biology in the Skin" in Molecular Biology of the Cell, commissioned review
 
Poster - SID Annual Mtg., Atlanta, GA – May 2015
-- FRA1 plays an essential role in skin, head and neck cancer cell growth and migration .
--NuMA/microtubule interactions are critical for asymmetric cell divisions and epidermal morphogenesis.
Lai C, August S, Albibas A, Behar R, Cho SY, Polak ME, Theaker J, MacLeod AS, French RR, Glennie M, Al-Shamkhani A, Healy E. O40+ regulatory T cells in cutaneous squamous cell carcinoma suppress effector T cell responses and associate with metastatic potential.  Accepted 2016 in Clinical Cancer Research.
 
Chen Y, Fang Q, Zang Z, Zhang Y, MacLeod AS, Hall RP, Liedtke W.  Transient receptor potential vanilloid 4 ion channel functions as a pruriceptor in epidermal keritinocytes to evoke histaminergic itch.  First published on 2016 Mar 9. doi: 10.1074/jbc.M116.716464
 
Poster -- SID Annual Mtg., Atlanta, GA – May 2015
-- ENTPD1 and PD-1/PD-1 ligands are highly expressed by skin-resident immune cells in subsets of human SCC.
 
MacLeod AS, Mansbridge, JN. The Innate Immune System in Acute and Chronic Wounds.  Advances in Wound Care. eprint 2015 Mar 25.  doi: 10.1089/wound.2014.0608.
 
Poster - SID Annual Mtg., Atlanta, GA – May 2015
-- FRA1 plays an essential role in skin, head and neck cancer cell growth and migration.
--ENTPD1 and PD-1/PD-1 ligands are highly expressed by skin-resident immune cells in subsets of human SCC.
--miR29b1 plays an important role in epidermal cell growth and survival. 
 
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